Manifestações da infecção pelo novo vírus influenza A (H1N1) na tomografia computadorizada de tórax / Manifestations of infection by the novel influenza A (H1N1) virus at chest computed tomography

OBJETIVO: Descrever as alterações na tomografia computadorizada de tórax de casos comprovados de infecção pelo novo vírus influenza A (H1N1). MATERIAIS E MÉTODOS: Três observadores avaliaram, em consenso, nove tomografias computadorizadas de pacientes com infecção pelo vírus influenza A (H1N1) comprovada laboratorialmente. A idade dos pacientes variou de 14 a 64 anos (média de 40 anos), sendo cinco do sexo masculino e quatro do sexo feminino. Quatro pacientes eram previamente hígidos, quatro eram transplantados renais e uma era gestante à época do diagnóstico. Foram avaliadas a presença, a extensão e a distribuição de: a) opacidades em vidro fosco; b) nódulos centrolobulares; c) consolidações; d) espessamento de septos interlobulares; e) derrame pleural; f) linfonodomegalias. RESULTADOS: As alterações mais frequentemente encontradas foram opacidades em vidro fosco, nódulos centrolobulares e consolidações, presentes em nove (100 por cento), cinco (55 por cento) e quatro (44 por cento) dos casos, respectivamente. Derrames pleurais e linfonodomegalias foram menos comuns, ocorrendo em apenas dois (22 por cento) dos casos estudados. CONCLUSÃO: Os achados mais comuns nos casos de infecção pelo novo vírus influenza A (H1N1) foram opacidades em vidro fosco, nódulos centrolobulares e consolidações. Estas alterações não são típicas ou únicas a este agente, podendo ocorrer também em outras infecções virais ou bacterianas.

OBJECTIVE: The objective of this study was to describe chest computed tomography findings in confirmed cases of infection by the novel influenza A (H1N1) virus. MATERIALS AND METHODS: Computed tomography studies of nine patients with laboratory-confirmed infection by the novel influenza A (H1N1) virus were consensually evaluated by three observers. The sample of the present study included five male and four female patients with ages ranging from 14 to 64 years (mean, 40 years). Four of the patients were previously healthy, four were kidney transplant recipients and one was pregnant at the time of diagnosis. Presence, extent and distribution of the following findings were evaluated: a) ground-glass opacities; b) centrilobular nodules; c) consolidation; d) interlobular septa thickening; e) pleural effusion; f) lymphadenopathy. RESULTS: The most frequent findings were ground-glass opacities, centrilobular nodules and consolidations, present in nine (100 percent), five (55 percent) and four (44 percent) of cases, respectively. Pleural effusions and lymphadenopathy were less common findings, occurring in only two (22 percent) of the cases. CONCLUSION: Ground-glass opacities, centrilobular nodules and consolidation were the most frequent findings in cases of infection by the novel influenza A (H1N1) virus. These changes are not typical or unique to this agent and may also occur in other viral or bacterial infections.

Avian influenza [AI] in Egypt: understanding risk factors

The Ministry of Health and Population [MOH and P] of Egypt has reported a new confirmed human case of avian influenza [AI] [case number 57] on 4 March 2009. The new case is a boy, two and a half year old from Ammaria District, Alexandria Governorate. Investigations into the source of infection confirmed history of close contact with dead and sick poultry prior to becoming ill. This brings up the total number of human confirmed cases of AI in Egypt to 57 with 23 deaths CFR=40.3%]

Grippe aviaire; comment se proteger?

La Grippe aviaire affection virale respiratoire aigue causee par le virus enveloppe a ARN. Certains virus de la grippe s'attaquent aux animaux; dont les oiseaux (grippe aviaire) et d'autres aux humains (grippe saisonniere). Ce qui est nouveau; c'est qu'on observe des virus d'oiseaux qui se transmettent aux humains. Nous avons recueilli des informations sur la grippe aviaire pour permettre aux soignants de mieux comprendre les nouvelles menaces qui pesent sur l'espece humaine